A key deliverable for the Biologics Development and Biologics Manufacturing Sciences & Technology organizations at Bristol-Myers Squibb is to generate and document process knowledge that will inform the in-process control strategy for existing and/or eventual biologics manufacturing processes.
Three years ago, an investment was initiated to improve the process of (1) capturing data and then (2) transforming that data into process knowledge, particularly focused around the laboratory-scale production bioreactor unit operation, so that both organizations are able to deliver on the growing biologics pipeline more quickly, more efficiently, and more consistently.
The purpose of this talk is to showcase the result of this investment, the Biologics Analytics Tool, which is a Spotfire visualization serving upstream scientists that seamlessly aggregates and visualizes bioreactor-related data from the PI System with data from an Electronic Laboratory Notebook system and a Laboratory Information Management System.
In particular, the talk will focus on how PI Web API and the PI Integrator for Business Analytics were key enabling components that were leveraged to structure the data and then subsequently create the Biologics Analytics Tool.
Speaker
Sohan Patel
Sohan Patel is an Engineer I in the Upstream Late-Stage Biologics Development group at Bristol-Myers Squibb in Devens, MA. In addition to supporting upstream process development and process characterization activities, he has served as a business lead in deploying the PI System for laboratory-scale bioreactors and associated instruments and configuring the corresponding Asset Framework element templates and hierarchy. Sohan holds a BS in Chemical Engineering from University of California, Berkeley and a MSCEP (MS in Chemical Engineering Practice) from Massachusetts Institute of Technology.